- Salem (Population: 2,006)
- Shady Spring (Population: 2,078)
- Shinnston (Population: 2,295)
- Sissonville (Population: 4,399)
- Sistersville (Population: 1,588)
- Sophia (Population: 1,301)
- South Charleston (Population: 13,390)
- Spencer (Population: 2,352)
- St. Albans (Population: 11,567)
- St. Marys (Population: 2,017)
- Stanaford (Population: 1,443)
- Star City (Population: 1,366)
- Stonewood (Population: 1,815)
- Summersville (Population: 3,294)
- Sutton (Population: 1,011)
- Switzer (Population: 1,138)
